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Rat Model for Leukopenia (LK)

Leukocytopenia; Leucopenia

  • Product No.DSI537Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by cyclophosphamide
  • Model Animal StrainsWistar Rats(SPF), healthy, male, body weight 180g~200g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
  • Modeling Method"Weight about 150 g SD rats, according to the dose of 30 mg/kg body weight after the intraperitoneal injection of cyclophosphamide, continuous injection of 5 d. Model rats in drug delivery, drug delivery, 3, 5 days before and after drug withdrawal,5,8,11,15 2, respectively, in pursuance of a peripheral blood test, observe the total number of peripheral blood leukocytes. The last one test observation anesthesia executed after animals, take its femur, flush with Hanks liquid bone marrow cell, a microscope bone marrow nucleated cell count."
  • Applicationsn/a
  • Downloadn/a
  • UOM Each case
  • FOB US$ 200 
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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DSI537Ra01 Rat Model for Leukopenia (LK) n/a