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Cavia Model for Pruritus

Itch

  • Product No.DSI594Gu01
  • Organism SpeciesCavia (Guinea pig ) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by histamine phosphate injection
  • Model Animal StrainsGuinea pig, healthy, male and female, body weight 350g~700g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
  • Modeling Method2d before the experiment, cut off the guinea pig's right hind foot hair, remove the hair with the hair rmoval agent, about 1cm2, the day of the experiment, scratche gently the hair removal of the skin with a fine sandpaper , make it red, 30min after the scratch area, smear 0.05% phosphoric acid histamine <30ul / only), in 3min if the guinea pigs does not appear itching reaction, that is, after the right foot after the abrasion of the action, in the smear once histamine, repeat the operation until the itching reaction.
  • Applicationsn/a
  • Downloadn/a
  • UOM Each case
  • FOB US$  
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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INCREMENT SERVICES

Catalog No. Related products for research use of Cavia (Guinea pig ) Organism species Applications (RESEARCH USE ONLY!)
DSI594Gu01 Cavia Model for Pruritus n/a