Rabbit Model for Myocardiosis

Cardiomyopathy

  • Product No.DSI596Rb01
  • Organism SpeciesOryctolagus cuniculus (Rabbit) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by intraperitoneal injectionn of adriamyein
  • Model Animal StrainsJapanese white rabbit, healthy, male and female, weight 1.5-2.5kg.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group(low,medium,high).
  • Modeling Periodn/a
  • Modeling MethodJapanese big ear rabbit, weight 1.5 ~ 2.5 kg, age 3 ~ 4 months, inject the adriamycin veining the rabbit ear margin, 1 mg/kg each time, 2 times a week, a total of eight weeks, roughly equivalent to 320 mg / ㎡, adriamycin diluted with normal saline (NS) into 1 mg/ml. In order to avoid the heart adriamycin acute poisoning effect interference, after building to be put to death animals and part of the myocardial tissue for histological observation. (1) the determination of echocardiography: the determination of chest wall left cardiac structure and function of experimental animals. (2) the cardiac morphological observation: left ventricular myocardial tissue, 10% formaldehyde (formaldehyde) liquid fixed, paraffin embedding, 5 microns section, HE staining, the pathological changes were observed under light K.
  • Applicationsn/a
  • Downloadn/a
  • UOM Each case
  • FOB US$  
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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Catalog No. Related products for research use of Oryctolagus cuniculus (Rabbit) Organism species Applications (RESEARCH USE ONLY!)
DSI596Rb01 Rabbit Model for Myocardiosis n/a
DSI596Rb02 Rabbit Model for Myocardiosis n/a