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Rat Model for Dental Caries (DC)

Tooth decay; Cavities

  • Product No.DSI809Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by injection of Streptococcus mutans into the oral cavity, combined with cariogenic diet
  • Model Animal StrainsSD rats (SPF), male, age: 5 weeks
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period10~12 weeks
  • Modeling Method1. For 4 days, the BHI bacteria liquid (100ul/) of S.Mutans in the oral cavity of rats was given once a day, once in the morning, and the water was forbidden within 30mins after inoculation.
    2. 41 days later, with the sterile scraping bamboo oral plaques, an anaerobic tank overnight culture, detect whether S.Mutans colonization. All rats were fed from 37 of the diet and fed a diet of 10% sucrose.
  • ApplicationsDisease Model
  • Downloadn/a
  • UOM Each case
  • FOB US$ 300 
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
DSI809Ra01 Rat Model for Dental Caries (DC) Disease Model