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Biotin-Linked Polyclonal Antibody to Serglycin (SRGN)

PRG; PPG; PRG1; proteoglycan 1, secretory granule

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SRGN. It has been selected for its ability to recognize SRGN in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Irish Journal of Medical Science The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis Pubmed: 30536194
MOLECULAR AND CELLULAR BIOCHEMISTRY SRGN, a new identified shear-stress-responsive gene in endothelial cells Pubmed: 32712749
Theranostics Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer 33456569
CELLULAR ONCOLOGY Cancer©\associated fibroblasts secrete hypoxia©\induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by ¡­ 33651283
Cell Death Dis Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone 34556636
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