Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)

MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin

Product No.MAA684Hu27
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourceMonoclonal antibody preparation
HostMouse
Potency (Clone Number)D1
Ig Isotype IgG1 Kappa
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPA684Hu02-Recombinant Mucin 5 Subtype B (MUC5B)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid
Concentration1mg/mL
Organism Species Moren/a
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
DownloadInstruction Manual
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 113 263 US$ 263 US$ 375 US$ 938 US$ 3750
For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against MUC5B. It has been selected for its ability to recognize MUC5B in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine	Citations
The Journal of Biological Chemistry	The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling Jcb: 34199
The Journal of Biological Chemistry	The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling Jcb: 247684
Respiratory Researh	Pyocyanin-induced mucin production is associated with redox modification of FOXA2 PubMed: PMC3765780
Respirology	Secreted mucins and airway bacterial colonization in non-CF bronchiectasis PubMed: 26172851
American Thoracic Society International Conference Abstracts	Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness doi:10.1164
Ann Am Thorac Soc	Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization doi:10.1513
	Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой 10.20538/1682-0363-2017-2-146-158
Allergy	Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps Pubmed:29802623
European Journal of Pharmacology	Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Pubmed:29382534
Japan Society of Immunology & Allergology in Otolaryngology	インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 10.5648:jjiao.36.7
Journal of Investigative Medicine	The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease Pubmed: 30573494
Mucosal Immunology	ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism Pubmed: 31278375

Catalog No.	Related products for research use of Homo sapiens (Human) Organism species	Applications (RESEARCH USE ONLY!)
RPA684Hu02	Recombinant Mucin 5 Subtype B (MUC5B)	Positive Control; Immunogen; SDS-PAGE; WB.
RPA684Hu01	Recombinant Mucin 5 Subtype B (MUC5B)	Positive Control; Immunogen; SDS-PAGE; WB.
CPA684Hu21	OVA Conjugated Mucin 5 Subtype B (MUC5B)	Immunogen; SDS-PAGE; WB.
PAA684Hu01	Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
PAA684Hu02	Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
LAA684Hu81	FITC-Linked Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IF.
LAA684Hu71	Biotin-Linked Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC.
MAA684Hu27	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
MAA684Hu28	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	IHC
MAA684Hu21	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
MAA684Hu22	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB
MAA684Hu23	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
MAA684Hu24	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
MAA684Hu25	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
MAA684Hu29	Monoclonal Antibody to Mucin 5 Subtype B (MUC5B)	WB; IHC; ICC; IP.
SEA684Hu	ELISA Kit for Mucin 5 Subtype B (MUC5B)	Enzyme-linked immunosorbent assay for Antigen Detection.
SCA684Hu	CLIA Kit for Mucin 5 Subtype B (MUC5B)	Chemiluminescent immunoassay for Antigen Detection.
LMA684Hu	Multiplex Assay Kit for Mucin 5 Subtype B (MUC5B) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.