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Monoclonal Antibody to Deoxyribonuclease I (DNASE1)

DNaseI; DNL1; DRNI; DNase-I; Dornase alfa

  • Product No.MAB127Bo21
  • Organism SpeciesBos taurus; Bovine (Cattle) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 126  US$ 294  US$ 420  US$ 1050  US$ 4200 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against DNASE1. It has been selected for its ability to recognize DNASE1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
J Card Fail Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure Pubmed:27349571
Biochimie Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of … Pubmed: 32315661
Scientific Reports Biomarkers of neutrophil extracellular traps (NETs) and nitric oxide-(NO)-dependent oxidative stress in women who miscarried Pubmed: 32753622
J Am Heart Assoc DNase 1 Protects From Increased Thrombin Generation and Venous Thrombosis During Aging: Cross‐Sectional Study in Mice and Humans Pubmed:35023342
Catalog No. Related products for research use of Bos taurus; Bovine (Cattle) Organism species Applications (RESEARCH USE ONLY!)
RPB127Bo01 Recombinant Deoxyribonuclease I (DNASE1) Positive Control; Immunogen; SDS-PAGE; WB.
PAB127Bo01 Polyclonal Antibody to Deoxyribonuclease I (DNASE1) WB; IHC; ICC; IP.
MAB127Bo21 Monoclonal Antibody to Deoxyribonuclease I (DNASE1) WB; IHC; ICC; IP.
SEB127Bo ELISA Kit for Deoxyribonuclease I (DNASE1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB127Bo Multiplex Assay Kit for Deoxyribonuclease I (DNASE1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.