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Monoclonal Antibody to Interleukin 31 (IL31)

  • Product No.MAB179Hu22
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 106  US$ 246  US$ 352  US$ 880  US$ 3520 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against IL31. It has been selected for its ability to recognize IL31 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
allergy and clinical immunology Increased serum levels of Interleukin-31 could modulate inflammatory processes in multiple sclerosis Siaic-Review:Source
BMC Immunol Increased levels of interleukin 31 (IL-31) in osteoporosis PubMed: 2644965
Sci Rep. Interleukin-31 expression and relation to disease severity in human asthma pmc:PMC4783779
Exp Dermatol. Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice. pubmed:28191683
Nat Commun.  The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. pubmed:28067314
Experimental Dermatology Immediate-type allergic and protease-media ted reactions are involved in scratching behavior induced by topical application of Dermatophagoides farinae extract in NC/Nga mice doi:10.1111
アトピー性皮膚炎の痒みの発症機序に関する研究
Indian Journal of Public Health Research & Development Determination the Role of Interleukin 31 (IL-31) Levels in Three Real Allergic Diseases (Asthma, Rhinitis, Urticaria)
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APB179Hu01 Active Interleukin 31 (IL31) Cell culture; Activity Assays.
RPB179Hu01 Recombinant Interleukin 31 (IL31) Positive Control; Immunogen; SDS-PAGE; WB.
PAB179Hu01 Polyclonal Antibody to Interleukin 31 (IL31) WB; IHC; ICC; IP.
MAB179Hu22 Monoclonal Antibody to Interleukin 31 (IL31) WB; IHC; ICC; IP.
SEB179Hu ELISA Kit for Interleukin 31 (IL31) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB179Hu CLIA Kit for Interleukin 31 (IL31) Chemiluminescent immunoassay for Antigen Detection.
LMB179Hu Multiplex Assay Kit for Interleukin 31 (IL31) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.