Monoclonal Antibody to Cluster Of Differentiation 83 (CD83)

BL11; HB15; Activated B Lymphocytes,Immunoglobulin; B-cell activation protein; Cell surface protein HB15

Product No.MAB845Mu21
Organism SpeciesMus musculus (Mouse) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourceMonoclonal antibody preparation
HostMouse
Potency (Clone Number)C10
Ig Isotype IgG2b Kappa
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPB845Mu01-Recombinant Cluster Of Differentiation 83 (CD83)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid
Concentration0.82mg/ml
Organism Species MoreRattus norvegicus (Rat)
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
DownloadInstruction Manual
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 109 253 US$ 253 US$ 362 US$ 905 US$ 3620
For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CD83. It has been selected for its ability to recognize CD83 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-3µg/mL
Immunohistochemistry: 5-30µg/mL
Immunocytochemistry: 5-30µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine	Citations
Immunobiology.	Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo Pubmed:25151500
PLoS One	The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro PubMed: 26619195
Scientific Reports COMMUNICATIONS	NK cells are negatively regulated by sCD83 in experimental autoimmune uveitis pubmed:29038541
Frontiers in Immunology	A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice. pubmed:28491062
Frontiers in Immunology	Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells Pubmed:30050530
THERIOGENOLOGY	Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasion Pubmed: 32810792

Catalog No.	Related products for research use of Mus musculus (Mouse) Organism species	Applications (RESEARCH USE ONLY!)
RPB845Mu01	Recombinant Cluster Of Differentiation 83 (CD83)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB845Mu02	Recombinant Cluster Of Differentiation 83 (CD83)	Positive Control; Immunogen; SDS-PAGE; WB.
PAB845Mu02	Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)	WB; IHC; ICC; IP.
PAB845Mu01	Polyclonal Antibody to Cluster Of Differentiation 83 (CD83)	WB; IHC; ICC; IP.
MAB845Mu21	Monoclonal Antibody to Cluster Of Differentiation 83 (CD83)	WB; IHC; ICC; IP.
SEB845Mu	ELISA Kit for Cluster Of Differentiation 83 (CD83)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMB845Mu	Multiplex Assay Kit for Cluster Of Differentiation 83 (CD83) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.