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Monoclonal Antibody to Glutamine synthetase (GS)

GLNS; GLUL; Glutamate-Ammonia Ligase; Glutamate decarboxylase

  • Product No.MAD761Hu21
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 111  US$ 259  US$ 370  US$ 925  US$ 3700 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against GS. It has been selected for its ability to recognize GS in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
The FASEB Journal Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease pubmed:27511944
Annals of Neurology  High complement levels in astrocyte‐derived exosomes of Alzheimer disease Pubmed:29406582
Journal of Neuroscience Sex differences in the glutamate signaling pathway in juvenile rats Pubmed:28861894
FASEB Journal Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer disease Pubmed:29924942
Hepatology Research Glutamine synthetase promotes tumor invasion in hepatocellular carcinoma through mediating epithelial–mesenchymal transition Pubmed: 31652385
FASEB JOURNAL Traumatic brain injury increases plasma astrocyte‐derived exosome levels of neurotoxic complement proteins Pubmed: 31916313
Translational Psychiatry Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis Pubmed: 33106473
Drug Repurposing of Asparaginase and Vitamin C Targeting Glutamine Synthetase Improves Anticancer Effect in Metastatic Castration-resistant Prostate …
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPD761Hu01 Recombinant Glutamine synthetase (GS) Positive Control; Immunogen; SDS-PAGE; WB.
PAD761Hu01 Polyclonal Antibody to Glutamine synthetase (GS) WB; IHC; ICC; IP.
LAD761Hu71 Biotin-Linked Polyclonal Antibody to Glutamine synthetase (GS) WB; IHC; ICC.
LAD761Hu81 FITC-Linked Polyclonal Antibody to Glutamine synthetase (GS) WB; IHC; ICC; IF.
MAD761Hu21 Monoclonal Antibody to Glutamine synthetase (GS) WB; IHC; ICC; IP.
SED761Hu ELISA Kit for Glutamine synthetase (GS) Enzyme-linked immunosorbent assay for Antigen Detection.
LMD761Hu Multiplex Assay Kit for Glutamine synthetase (GS) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.