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Monoclonal Antibody to Fibulin 3 (FBLN3)

EFEMP1; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; EGF-Containing Fibulin-Like Extracellular Matrix Protein 1; Fibrillin-Like; Extracellular protein S1-5

  • Product No.MAF422Hu23
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)14#
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 112  US$ 261  US$ 373  US$ 933  US$ 3730 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against FBLN3. It has been selected for its ability to recognize FBLN3 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
1 Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma PubMed: PMC3761217
Anticancer Res. YKL-40 and mesothelin in the blood of patients with malignant mesothelioma, lung cancer and asbestosis. Pubmed: 24324091
Oncology Reports Role of fibulin-3 in lung cancer: In vivo and in vitro analyses Spandidos-publications: Source
Current Pulmonology Reports Discovery of new biomarkers for malignant mesothelioma Springer:Source
United States Patent Application 20140378336 DIAGNOSIS OF CELL PROLIFERATIVE DISEASES Freepatentsonline:Source
Thorax. Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma Pubmed:Pmc4174124
Egyptian Journal of Chest Diseases and Tuberculosis Value of plasma and pleural effusion fibulin-3 levels in the diagnosis of malignant pleural mesothelioma effusions Pubmed:23050525
Radiol Oncol Fibulin-3 as a biomarker of response to treatment in malignant mesothelioma PubMed: 26401134
British Journal of Cancer Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis PubMed: 26263483
J Thorac Oncol. Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma. Pubmed:26903362
BMJ Open Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational study pubmed:27884852
25 HMGB1 and its hyperacetylated isoform are sensitive and specific serum biomarkers to detect asbestos exposure and to identify mesothelioma patients pubmed:26733616
BMJ Journals Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational … e013324.abstract
Anticancer Res. Comparison of the Diagnostic Performance of Fibulin-3 and Mesothelin in Patients with Pleural Effusions from Malignant Mesothelioma. pubmed:28314308
Dis Markers. A Novel Panel of Serum Biomarkers for MPM Diagnosis. pubmed:28348450
The Knee Association of fibulin-3 concentrations with the presence and severity of knee osteoarthritis: A cross-sectional study pubmed:29195846
Disease markers Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population pubmed:29200597
Molecular Medicine Reports Placental protein 14 as a potential biomarker for diagnosis of preterm premature rupture of membranes Pubmed:29749501
Oncotarget The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion Pubmed:30046386
Advances in Clinical and Experimental Medicine Fibulin-3 and other cartilage metabolism biomarkers in relationship to calprotectin (MRP8/14) and disease activity in rheumatoid arthritis patients treated with … 68362.pdf
PLoS One Prediction of pneumoconiosis by serum and urinary biomarkers in workers exposed to asbestos-contaminated minerals Pubmed: 30946771
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPF422Hu02 Recombinant Fibulin 3 (FBLN3) Positive Control; Immunogen; SDS-PAGE; WB.
RPF422Hu01 Recombinant Fibulin 3 (FBLN3) Positive Control; Immunogen; SDS-PAGE; WB.
PAF422Hu01 Polyclonal Antibody to Fibulin 3 (FBLN3) WB; IHC; ICC; IP.
PAF422Hu02 Polyclonal Antibody to Fibulin 3 (FBLN3) WB; IHC; ICC; IP.
LAF422Hu71 Biotin-Linked Polyclonal Antibody to Fibulin 3 (FBLN3) WB; IHC; ICC.
MAF422Hu23 Monoclonal Antibody to Fibulin 3 (FBLN3) WB; IHC; ICC; IP.
MAF422Hu24 Monoclonal Antibody to Fibulin 3 (FBLN3) WB; IHC; ICC; IP.
MAF422Hu22 Monoclonal Antibody to Fibulin 3 (FBLN3) WB
MAF422Hu25 Monoclonal Antibody to Fibulin 3 (FBLN3) WB
MAF422Hu21 Monoclonal Antibody to Fibulin 3 (FBLN3) WB
SEF422Hu ELISA Kit for Fibulin 3 (FBLN3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCF422Hu CLIA Kit for Fibulin 3 (FBLN3) Chemiluminescent immunoassay for Antigen Detection.
LMF422Hu Multiplex Assay Kit for Fibulin 3 (FBLN3) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.