Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)

CCL2; GDCF2; HC11; HSMCR30; MCAF; MCP1; SCYA2; SMC-CF; Chemokine C-C-Motif Ligand 2; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against MCP1. It has been selected for its ability to recognize MCP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
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Микроэлементы в медицине НАРУШЕНИЕ БАЛАНСА ХРОМА И ВАНАДИЯ В ЖИРОВОЙ ТКАНИ КАК ВОЗМОЖНЫЙ МЕХАНИЗМ ОЖИРЕНИЕ-АССОЦИИРОВАННОЙ ИНСУЛИНОРЕЗИСТЕНТНОСТИ Microelements_Of_Midicine: 2015_2
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Nature Medicine An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. pubmed:29227475
Redox Biology STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient. pubmed:29078168
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Catalog No. Related products for research use of Bos taurus; Bovine (Cattle) Organism species Applications (RESEARCH USE ONLY!)
RPA087Bo01 Recombinant Monocyte Chemotactic Protein 1 (MCP1) Positive Control; Immunogen; SDS-PAGE; WB.
APA087Bo61 Active Monocyte Chemotactic Protein 1 (MCP1) Cell culture; Activity Assays.
EPA087Bo61 Eukaryotic Monocyte Chemotactic Protein 1 (MCP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA087Bo01 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1) WB; IHC; ICC; IP.
CGA087Bo01 cDNA of Monocyte Chemotactic Protein 1 (MCP1) PCR; Protein Expression; etc.