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Polyclonal Antibody to Caveolin 1 (CAV1)

VIP21; Caveolae Protein 22kDa

  • Product No.PAA214Rb51
  • Organism SpeciesOryctolagus cuniculus (Rabbit) Same name, Different species.
  • SourcePolyclonal antibody preparation
  • HostGuinea pig
  • Potencyn/a
  • Ig Type IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelAPC
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration500µg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 103  US$ 239  US$ 342  US$ 855  US$ 3420 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a cavia polyclonal antibody raised against CAV1. It has been selected for its ability to recognize CAV1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Mendel Net Novel prostate cancer tumour markers in a cell line model Mendelu: source
Oncology reports Caveolin-1 as a potential high-risk prostate cancer biomarker PubMed: 22159333
Anticancer Research Increased plasma caveolin-1 levels are associated with progression of prostate cancer among Japanese men Pubmed: 23645736
Sarcoidosis Vasc Diffuse Lung Dis.? Decrased sputum caveolin-1 is associated with systemic sclerosis related lung disease Pubmed:24751454
Cancer Genomics and Proteomics Significant Association of Caveolin-1 and Caveolin-2 with Prostate Cancer Progression PubMed: 26543085
Atherosclerosis Genomic variant in CAV1 increases susceptibility to coronary artery disease and myocardial infarction Pubmed:26775120
Arthritis Research & Therapy Increased caveolin-1 in intervertebral disc degeneration facilitates repair Pubmed:26939667
Oxid Med Cell Longev Lower Serum Caveolin-1 Is Associated with Cerebral Microbleeds in Patients with Acute Ischemic Stroke Pubmed:27119011
Inflammation Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive PulmonaryDisease. pubmed:27613621
Oxidative Medicine and Cellular Longevity Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice Pubmed:29849903
Microcirculation Endothelium‐dependent hyperpolarization‐mediated vasodilatation compensates nitric oxide‐mediated endothelial dysfunction during ischemia in diabetes‐induced … Pubmed:29665152
Genetic Testing and Molecular Biomarkers The CAV1 Gene 3′ Untranslated Region Single Nucleotide Polymorphisms Are Associated with the Risk of Pulmonary Hypertension in Chinese Han Chronic …
Cell Rep SIRT6 transcriptionally regulates fatty acid transport by suppressing PPAR¦Ã 34077730
researchsquare Cav-1 Protein Levels in Serum and Infarcted Brain Correlate with Hemorrhagic Volume in a Mouse Model of Thromboembolic Stroke, Independently of Rt-PA?¡­
Molecules 5, 2′-Dibromo-2, 4′, 5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 Protein Pubmed:35566232
Catalog No. Related products for research use of Oryctolagus cuniculus (Rabbit) Organism species Applications (RESEARCH USE ONLY!)
RPA214Rb01 Recombinant Caveolin 1 (CAV1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA214Rb51 Polyclonal Antibody to Caveolin 1 (CAV1) WB; IHC; ICC; IP.