Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)

ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against bACE1. It has been selected for its ability to recognize bACE1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Food & Function Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice pubmed:29292421
Journal of Functional Foods EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation 10.1016/j.jff.2017.12.016
Journal of Nutritional Biochemistry Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet Pubmed:29986309
Neurotoxicology Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
Food Chem Toxicol Effects of Alcohol Intake on Cognitive Function and ¦Â-amyloid Protein in APP/PS1 Transgenic Mice 33737111
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPA718Hu01 Recombinant Beta-Site APP Cleaving Enzyme 1 (bACE1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA718Hu01 Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB; IHC; ICC; IP.
MAA718Hu23 Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB; IHC; ICC; IP.
MAA718Hu24 Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB; IHC; ICC; IP.
MAA718Hu25 Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB; IHC; ICC; IP.
MAA718Hu22 Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB
MAA718Hu21 Monoclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1) WB; IHC; ICC; IP.
SEA718Hu ELISA Kit for Beta-Site APP Cleaving Enzyme 1 (bACE1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA718Hu Multiplex Assay Kit for Beta-Site APP Cleaving Enzyme 1 (bACE1) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSA718Hu01 ELISA Kit DIY Materials for Beta-Site APP Cleaving Enzyme 1 (bACE1) Main materials for "Do It(ELISA Kit) Yourself"