Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1)

HIRS1

Product No.PAC546Mu02
Organism SpeciesMus musculus (Mouse) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourcePolyclonal antibody preparation
HostRabbit
Potencyn/a
Ig Type IgG
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
LabelNone
Immunogen RPC546Mu02-Recombinant Insulin Receptor Substrate 1 (IRS1)
Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
TraitsLiquid
Concentration500µg/mL
Organism Species Moren/a
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
Downloadn/a
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 108 252 US$ 252 US$ 360 US$ 900 US$ 3600
For more details, please contact local distributors!

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against IRS1. It has been selected for its ability to recognize IRS1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine	Citations
МЕДИЦИНСКИЙ ВЕСТНИК СЕВЕРНОГО КАВКАЗА	Сравнительный анализ уровней антител к инсулиновым рецепторам у детей с сахарным диабетом i типа в зависимости от стадии заболевания article:n
Eur Neuropsychopharmacol.	Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment. pubmed:28063625
Diabetes	Lack of brain insulin receptor substrate-1 causes growth retardation, with decreased expression of growth hormone-releasing hormone in the hypothalamus. 33980693

Catalog No.	Related products for research use of Mus musculus (Mouse) Organism species	Applications (RESEARCH USE ONLY!)
RPC546Mu01	Recombinant Insulin Receptor Substrate 1 (IRS1)	Positive Control; Immunogen; SDS-PAGE; WB.
RPC546Mu02	Recombinant Insulin Receptor Substrate 1 (IRS1)	Positive Control; Immunogen; SDS-PAGE; WB.
PAC546Mu01	Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1)	WB; IHC; ICC; IP.
PAC546Mu02	Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1)	WB; IHC; ICC; IP.
LAC546Mu81	FITC-Linked Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1)	WB; IHC; ICC; IF.
SEC546Mu	ELISA Kit for Insulin Receptor Substrate 1 (IRS1)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMC546Mu	Multiplex Assay Kit for Insulin Receptor Substrate 1 (IRS1) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.

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