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Recombinant Lipopolysaccharide Binding Protein (LBP)

LPS-Binding Protein

  • Product No.RPB406Po03
  • Organism SpeciesSus scrofa; Porcine (Pig) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationExtracellular matrix
  • Predicted Molecular Mass66.5kDa
  • Accurate Molecular Mass67kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsn36~Thr474 with Two N-terminal Tags, His-tag and SUMO-tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 80%
  • Isoelectric Point6.0
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 198  US$ 495  US$ 990  US$ 2970  US$ 7425 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
37 A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese Diabetes: source
AIDS Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy PubMed: PMC3754419
31 Gut microbiome composition is linked to whole grain-induced immunological improvements Pubmed: 23038174
The Veterinary Journal High ambient temperature alleviates the inflammatory response and growth depression in pigs challenged with Escherichia coli lipopolysaccharide Pubmed: 24792207
Perfusion The effect of normovolemic modified ultrafiltration on inflammatory mediators, endotoxins, terminal complement complexes and clinical outcome in high-risk cardiac surgery patients Pubmed: 23429100
FEMS Microbiology Ecology A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome. Pubmed: 24117923
Digestive diseases and sciences Frequency and Severity of Cirrhotic Cardiomyopathy and Its Possible Relationship with Bacterial Endotoxemia Pubmed: 23907333
Atherosclerosis Circulating pathogen associated molecular pattern – Binding proteins and High Mobility Group Box protein 1 in nascent metabolic syndrome: Implications for cellular Toll-like receptor activity Pubmed:25063948
BMC Complementary and Alternative Medicine Identification of plasma protein markers common to patients with malignant tumour and Abnormal Savda in Uighur medicine: a prospective clinical study Pubmed:25652121
Atherosclerosis Increased adipose tissue secretion of Fetuin-A, lipopolysaccharide-binding protein and high-mobility group box protein 1 in metabolic syndrome PubMed: 25978344
Annals of Gastroenterology Systemic levels of human β-defensin 1 are elevated in patients with cirrhosis PubMed: 26751578
Food Chem. Comparative proteomics of milk fat globule membrane in goat colostrum and mature milk Pubmed:27173528
Liver International High serum lipopolysaccharide binding protein is associated with increased mortality in patients with decompensated cirrhosis pubmed:27712029
Journal of Functional Foods Modulation of gut microbiota and gut-generated metabolites by bitter melon results in improvement in the metabolic status in high fat diet-induced obese rats 10.1016/j.jff.2017.12.050
Scientific Reports Adamdec1, Ednrb and Ptgs1/Cox1, inflammation genes upregulated in the intestinal mucosa of obese rats, are downregulated by three probiotic strains. pubmed:28512356
Journal of ethnopharmacology A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2: A randomized, controlled, crossover trial. pubmed:28750942
Journal of Allergy and Clinical Immunology On a Western diet, APOE ɛ4 is associated with low innate immune sensing, but not APOE ɛ3 Pubmed:29928926
Journal of Animal Sciences Influence of yeast culture and feed antibiotics on ruminal fermentation and site and extent of digestion in beef heifers fed high grain rations Pubmed:30060086
Journal of Animal Science Using ruminally protected and nonprotected active dried yeast as alternatives to antibiotics in finishing beef steers: growth performance, carcass traits, blood … Pubmed: 30184125
BMC Complementary and Alternative Medicine Evaluation of the effect of Lactobacillus reuteri V3401 on biomarkers of inflammation, cardiovascular risk and liver steatosis in obese adults with metabolic … Pubmed: 30453950
Cell Communication and Signaling Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways
Nutrients High-dose Glycerol Monolaurate Up-Regulated Beneficial Indigenous Microbiota without Inducing Metabolic Dysfunction and Systemic Inflammation: New Insights …
Journal of Animal Science Ruminally protected and unprotected Saccharomyces cerevisiae fermentation products as alternatives to antibiotics in finishing beef steers Pubmed: 31410465
Nutrients Lactobacillus reuteri V3401 Reduces Inflammatory Biomarkers and Modifies the Gastrointestinal Microbiome in Adults with Metabolic Syndrome: The PROSIR Study Pubmed: 31370223
journal of veterinary pharmacology and therapeutics Effects of sinomenine in LPS‐associated diseases are related to inhibition of LBP, Mac‐1, and L‐selectin levels Pubmed: 31490576
Amyloid Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein Pubmed: 31615282
Food Research International Ethanol Extract of Propolis Prevents High-Fat Diet-Induced Insulin Resistance and Obesity in Association with Modulation of Gut Microbiota in Mice Pubmed: 32156386
Journal of Translational Medicine Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation Pubmed: 33036625
Communications Biology Oxidation of fish oil exacerbates alcoholic liver disease by enhancing intestinal dysbiosis in mice Pubmed: 32879433
MOLECULAR NUTRITION & FOOD RESEARCH Antibiotic Treatment Reduces the Health Benefits of Soy Protein Pubmed: 32729948
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced Obesity Pubmed: 32633953
fish & shellfish immunology Molecular characterization and expression analysis of chemokine (CXCL12) from Nile tilapia (Oreochromis niloticus) Pubmed: 32540504
Scientific Reports Tandem Mass Tag (TMT)-based quantitative proteomics reveals potential targets associated with onset of Sub-clinical Mastitis in cows Pubmed: 32518370
experimental eye research Corneal epithelial injury-induced norepinephrine promotes Pseudomonas aeruginosa keratitis Pubmed: 32376471
Frontiers in Microbiology Naringin Attenuates High Fat Diet Induced Non-alcoholic Fatty Liver Disease and Gut Bacterial Dysbiosis in Mice
Journal of Burn Care & Research Umbilical cord mesenchymal stem cells (hUCMSCs) for inflammatory regulation after excision and grafting of severe burn wounds in rats 33313794
JOURNAL OF ANIMAL SCIENCE Processing Index of Barley Grain and Dietary Undigested Neutral Detergent Fiber Concentration Affected Chewing Behavior, Ruminal pH and Total Tract Nutrient?¡­ 33474564
journal of agricultural and food chemistry Influence of a Biotechnologically Produced Oyster Mushroom (Pleurotus sajor-caju) on the Gut Microbiota and Microbial Metabolites in Obese Zucker Rats 33497213
JOURNAL OF HAZARDOUS MATERIALS Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and intestinal microbiota-independent manner 33582472
Doctoral Thesis Studies on Mastitis Caused by Translocated-Bacterial Components in Ruminants
Arthritis Res Ther Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint 34560894
Microorganisms Composition and Functions of the Gut Microbiome in Pediatric Obesity: Relationships with Markers of Insulin Resistance 34361925
Antioxidants The Prebiotic Potential of Geraniin and Geraniin-Enriched Extract against High-Fat-Diet-Induced Metabolic Syndrome in Sprague Dawley Rats Pubmed:35453317
Microbiome Elucidating the role of the gut microbiota in the physiological effects of dietary fiber Pubmed:35562794
Bioscience of Microbiota Food and Health Local free fatty acids trigger the expression of lipopolysaccharide-binding protein in murine white adipose tissue Pubmed:35433160
Siberian Medical Review Сorrelation between the level of 25 (OH) D3 in blood, the content of antimicrobial peptides in oral fluid and dental caries intensity in young individuals
Catalog No. Related products for research use of Sus scrofa; Porcine (Pig) Organism species Applications (RESEARCH USE ONLY!)
APB406Po02 Active Lipopolysaccharide Binding Protein (LBP) Cell culture; Activity Assays.
RPB406Po03 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
RPB406Po02 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
RPB406Po01 Recombinant Lipopolysaccharide Binding Protein (LBP) Positive Control; Immunogen; SDS-PAGE; WB.
PAB406Po01 Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
MAB406Po21 Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP) WB; IHC; ICC; IP.
SEB406Po ELISA Kit for Lipopolysaccharide Binding Protein (LBP) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB406Po Multiplex Assay Kit for Lipopolysaccharide Binding Protein (LBP) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.