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Recombinant Proteinase 3 (PR3)

MBN; PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Myeloblastin; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen

  • Product No.RPB434Hu01
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass20.8kDa
  • Accurate Molecular Mass21&17kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis71~Leu247 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point6.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 180  US$ 450  US$ 900  US$ 2700  US$ 6750 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
BioMed Research International Volume Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis? Pubmed:24949444
electronic thesis and dissertation repository Regulation of Leukocyte-Derived Matrix Metalloproteinases and Azurophilic Enzymes in Human Diabetic Ketoacidosis Etd: 2869
United States Patent Application DIAGNOSIS AND THERAPY OF CHRONIC INFLAMMATION-INDUCED DISORDERS y2016:0011207.html
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB434Hu02 Recombinant Proteinase 3 (PR3) Positive Control; Immunogen; SDS-PAGE; WB.
RPB434Hu01 Recombinant Proteinase 3 (PR3) Positive Control; Immunogen; SDS-PAGE; WB.
PAB434Hu01 Polyclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC; IP.
PAB434Hu02 Polyclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC; IP.
MAB434Hu22 Monoclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC; IP.
SEB434Hu ELISA Kit for Proteinase 3 (PR3) Enzyme-linked immunosorbent assay for Antigen Detection.
AEB434Hu ELISA Kit for Anti-Proteinase 3 Antibody (Anti-PR3) Enzyme-linked immunosorbent assay for Antibody Detection.
LMB434Hu Multiplex Assay Kit for Proteinase 3 (PR3) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.