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Recombinant Tyrosine Hydroxylase (TH)

TYH; DYT5b; Tyrosine 3-Monooxygenase; Dystonia 14

  • Product No.RPB438Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationCytoplasm
  • Predicted Molecular Mass37.1kDa
  • Accurate Molecular Mass37kDa(Analysis of differences refer to the manual)
  • Residues & TagsPhe34~Leu301 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point6.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 140  US$ 350  US$ 700  US$ 2100  US$ 5250 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Mol Neurobiol. 1, 25-dyhydroxyvitamin D3 Attenuates l-DOPA-Induced Neurotoxicity in Neural Stem Cells Pubmed:25102940
PLOS ONE Genetic Diagnosis of Two Dopa-Responsive Dystonia Families by Exome Sequencing Pubmed:25181484
biomedicine & pharmacotherapy Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. pubmed:28199883
Therapeutics and Clinical Risk Management Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population. pubmed:27540296
Sci Rep.  Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. pubmed:28230187
Journal of Cellular Biochemistry Vaccarin administration ameliorates hypertension and cardiovascular remodeling in renovascular hypertensive rats pubmed:28681939
Environmental Science & Technology Multigenerational disruption of the thyroid endocrine system in marine medaka after a life-cycle exposure to perfluorobutanesulfonate Pubmed:29565584
Molecular Neurobiology Cilostazol Mediated Nurr1 and Autophagy Enhancement: Neuroprotective Activity in Rat Rotenone PD Model Pubmed:29429051
Chemosphere Tetrabromobisphenol A caused neurodevelopmental toxicity via disrupting thyroid hormones in zebrafish larvae Pubmed:29407805
Neurospine The Effect of Recombinant Tyrosine Hydroxylase Expression on the Neurogenic Differentiation Potency of Mesenchymal Stem Cells Pubmed:29656620
Toxicology and Applied Pharmacology Montelukast attenuates rotenone-induced microglial activation/p38 MAPK expression in rats: Possible role of its antioxidant, anti-inflammatory and antiapoptotic effects Pubmed: 30222980
International Journal Of Cardiology Silencing salusin β ameliorates heart failure in aged spontaneously hypertensive rats by ROS-relative MAPK/NF-κB pathways in the paraventricular nucleus Pubmed: 30581101
Behavioural Brain Research Hydroxychloroquine antiparkinsonian potential: Nurr1 modulation versus autophagy inhibition
Environment International Perfluoropolyether carboxylic acids (novel alternatives to PFOA) impair zebrafish posterior swim bladder development via thyroid hormone disruption Pubmed: 31733528
Environmental Pollution Embryonic exposure to pentabromobenzene inhibited the inflation of posterior swim bladder in zebrafish larvae Pubmed: 31935612
International Journal of Pharmacology Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease Pubmed: 32084576
comparative biochemistry and physiology c-toxicology & pharmacology Thyroid disruption and developmental toxicity caused by Cd2+ in Schizopygopsis younghusbandi larvae Pubmed: 32344129
International Journal of Stem cell Research & Therapy Selection of Cells for Parkinson's Disease Cell-Therapy
Ecotoxicol Environ Saf Effects of SiO2 nanoparticles on the uptake of tetrabromobisphenol A and its impact on the thyroid endocrine system in zebrafish larvae 33385677
Nutr Res Tocotrienols protect differentiated SH-SY5Y human neuroblastoma cells against 6-hydroxydopamine-induced cytotoxicity by ameliorating dopamine biosynthesis and … Pubmed:35065349
Food Chem Toxicol Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation Pubmed:35439590
Food Chemistry: Molecular Sciences Unravelling the neuroprotective mechanisms of carotenes in differentiated human neural cells: biochemical and proteomic approaches Pubmed:35415676
Journal of Environmental Sciences Parental and transgenerational impairments of thyroid endocrine system in zebrafish by 2, 4, 6-tribromophenol
Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
RPB438Mu02 Recombinant Tyrosine Hydroxylase (TH) Positive Control; Immunogen; SDS-PAGE; WB.
RPB438Mu01 Recombinant Tyrosine Hydroxylase (TH) Positive Control; Immunogen; SDS-PAGE; WB.
PAB438Mu01 Polyclonal Antibody to Tyrosine Hydroxylase (TH) WB; IHC; ICC; IP.
PAB438Mu02 Polyclonal Antibody to Tyrosine Hydroxylase (TH) WB; IHC; ICC; IP.
SEB438Mu ELISA Kit for Tyrosine Hydroxylase (TH) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB438Mu Multiplex Assay Kit for Tyrosine Hydroxylase (TH) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.