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Recombinant Serotonin Transporter (SERT)

SLC6A4; SLC6-A4; HTT; 5-HTT; 5HTT; OCD1; hSERT; Solute Carrier Family 6,Member 4; Neurotransmitter Transporter,Serotonin; Sodium-dependent serotonin transporter

  • Product No.RPC890Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Endosome
  • Predicted Molecular Mass20.3kDa
  • Accurate Molecular Mass20kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer483~Val630 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 95%
  • Isoelectric Point5.8
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 184  US$ 460  US$ 920  US$ 2760  US$ 6900 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Journal of Prosthodontic Research Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control Pubmed:25127373
Frontiers in Behavioral Neuroscience? Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain Pubmed:25400562
Sleep Breath Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects PubMed: 26527205
PLoS One. Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived fromMouse P19 Embryonal Carcinoma Cells. pubmed:27861613
Herz-Hirn Interaktion im Mausmodell: Herzinsuffizienz nach Myokardinfarkt führt zu depressivem Verhalten bei Mäusen frontdoor:index
Effects of Junk Foods on Brain Neurotransmitters (Dopamine and Serotonin) and some Biochemical Parameters in Albino Rats article_1486_c0fa9f8afe5f70b407e7195bcfd55c70
Toxicology Reports Neuro-and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor … Pubmed:29854627
Journal of Taibah University for Science Neurotoxicity and inflammation induced by individual and combined exposure to iron oxide nanoparticles and silver nanoparticles
NEUROGASTROENTEROLOGY AND MOTILITY Effects of regulating gut microbiota on the serotonin metabolism in the chronic unpredictable mild stress rat model Pubmed: 31323174
Thrombosis Research VAMP8 and serotonin transporter levels are associated with venous thrombosis risk in a Spanish female population. Results from the RETROVE Project Pubmed: 31382081
Scientia Psychiatrica Neuronal Cell Death Induces Depressive Disorder in Rats Depression-Like Behaviors Caused by Chronic Stress
Journal of Immunology Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats 34568500
Biol Pharm Bull Targeting the oxytocin system to ameliorate early life depressive-like behaviors in maternally-separated rats 34349049
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPC890Ra01 Recombinant Serotonin Transporter (SERT) Positive Control; Immunogen; SDS-PAGE; WB.
PAC890Ra01 Polyclonal Antibody to Serotonin Transporter (SERT) WB; IHC; ICC; IP.
MAC890Ra21 Monoclonal Antibody to Serotonin Transporter (SERT) WB; IHC; ICC; IP.
SEC890Ra ELISA Kit for Serotonin Transporter (SERT) Enzyme-linked immunosorbent assay for Antigen Detection.
LMC890Ra Multiplex Assay Kit for Serotonin Transporter (SERT) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.
KSC890Ra01 ELISA Kit DIY Materials for Serotonin Transporter (SERT) Main materials for "Do It(ELISA Kit) Yourself"