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Recombinant Semaphorin 3A (SEMA3A)

SEMAL; Hsema-I; Hsema-III; SEMA1; SEMAD; SEMAIII; SemD; Coll-1; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 3A

  • Product No.RPL917Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Predicted Molecular Mass17.6kDa
  • Accurate Molecular Mass17kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg31~Pro150 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 90%
  • Isoelectric Point8.9
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 187  US$ 468  US$ 936  US$ 2808  US$ 7020 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Arthritis Research & Therapy Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus Biomed: ar3881
journal of invastigative dermatology Cathelicidin LL-37 Induces Semaphorin 3A Expression in Human Epidermal Keratinocytes: Implications for Possible Application to Pruritus PubMed: 26121211
Neurology Neurofilament light chain level is a weak risk factor for the development of MS. pubmed:27521440
Development miR-126-5p promotes retinal endothelial cell survival through SetD5 regulatio in neurons pubmed:29180574
A Preliminary Study of the Effect of Semaphorin 3A and Acitretin on the Proliferation, Migration, and Apoptosis of HaCaT Cells
Life Sciences Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway. Pubmed: 32603817
ACS NANO Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling Pubmed: 32413258
PLoS One Extract of Scutellaria baicalensis induces semaphorin 3A production in human epidermal keratinocytes 33905439
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
APL917Ra01 Active Semaphorin 3A (SEMA3A) Cell culture; Activity Assays.
RPL917Ra01 Recombinant Semaphorin 3A (SEMA3A) Positive Control; Immunogen; SDS-PAGE; WB.
PAL917Ra01 Polyclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
MAL917Ra21 Monoclonal Antibody to Semaphorin 3A (SEMA3A) WB; IHC; ICC; IP.
SEL917Ra ELISA Kit for Semaphorin 3A (SEMA3A) Enzyme-linked immunosorbent assay for Antigen Detection.
LML917Ra Multiplex Assay Kit for Semaphorin 3A (SEMA3A) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.