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Biotin-Linked Monoclonal Antibody to Cystatin B (CSTB)

Cys-B; CST6; EPM1; PME; STFB; CPI-B; Stefin B; Liver thiol proteinase inhibitor

SPECIFITY

The antibody is a mouse monoclonal antibody raised against CSTB. It has been selected for its ability to recognize CSTB in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
AIDS. Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders PubMed: 23291538
International Journal of Circumpolar Health Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancer PubMed: PMC3754495
PLoS One. Dysregulation of Macrophage-Secreted Cathepsin B Contributes to HIV-1-Linked Neuronal Apoptosis PubMed: PMC3365072
Journal of Neuroimmune Pharmacology Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages Pubmed:25209871
European Journal of Cancer Supplements A91: Endogenous inhibitors of cysteine proteases and preform of cathepsin B in cancer of reproductive system Science: Article
Annals of Clinical Biochemistry Diagnostic specificity and sensitivity of PIVKAII, GP3, CSTB, SCCA1 and HGF for the diagnosis of hepatocellular carcinoma in patients with alcoholic liver cirrhosis. pubmed:28766361
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