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Monoclonal Antibody to Proteinase 3 (PR3)

MBN; PRTN3; ACPA; AGP7; C-ANCA; MBT; P29; PRK; Myeloblastin; Serine Proteinase,Neutrophil,Wegener Granulomatosis Autoantigen

  • Product No.MAB434Ra21
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 115  US$ 267  US$ 382  US$ 955  US$ 3820 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against PR3. It has been selected for its ability to recognize PR3 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
BioMed Research International Volume Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis? Pubmed:24949444
electronic thesis and dissertation repository Regulation of Leukocyte-Derived Matrix Metalloproteinases and Azurophilic Enzymes in Human Diabetic Ketoacidosis Etd: 2869
United States Patent Application DIAGNOSIS AND THERAPY OF CHRONIC INFLAMMATION-INDUCED DISORDERS y2016:0011207.html
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB434Ra01 Recombinant Proteinase 3 (PR3) Positive Control; Immunogen; SDS-PAGE; WB.
PAB434Ra01 Polyclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC; IP.
LAB434Ra71 Biotin-Linked Polyclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC.
MAB434Ra21 Monoclonal Antibody to Proteinase 3 (PR3) WB; IHC; ICC; IP.
SEB434Ra ELISA Kit for Proteinase 3 (PR3) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB434Ra Multiplex Assay Kit for Proteinase 3 (PR3) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.