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Monoclonal Antibody to Glycogen Synthase Kinase 3 Beta (GSK3b)

Serine/threonine-protein kinase GSK3B

  • Product No.MAD317Hu21
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)n/a
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 111  US$ 259  US$ 370  US$ 925  US$ 3700 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against GSK3b. It has been selected for its ability to recognize GSK3b in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Neurological Research Sorafenib and lithium chloride combination treatment shows promising synergistic effects in human glioblastoma multiforme cells in vitro but midkine is not implicated Maneyonline:Source
 Int J Clin Exp Med Glycogen synthase kinase-3β (GSK-3β) rs334558 polymorphism is not associated with mild cognitive impairment in Chinese Han type 2 diabetic patients ijcem0038535.pdf
Bulletin of Experimental Biology and Medicine Signal Mechanism of the Protective Effect of Combined Preconditioning by Amtizole and Moderate Hypoxia Pubmed:29308565
Biomedicine & Pharmacotherapy Neuroprotective effects of Bergenia ciliata on NMDA induced injury in SH-SY5Y cells and attenuation of cognitive deficits in scopolamine induced amnesia in rats Pubmed: 30227331
FEATURES OF DISTRIBUTION OF SOYBEAN AGGLUTININ (SBA) RECEPTORS IN THE EXTRACELLULAR MATRIX OF THE MENISCI OF RAT KNEE JOINT …
Br J Haematol Glycogen synthase kinase 3β/CCR6‐positive bone marrow cells correlate with disease activity in multicentric Castleman disease‐TAFRO 34873687
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
APD317Hu01 Active Glycogen Synthase Kinase 3 Beta (GSK3b) Cell culture; Activity Assays.
RPD317Hu01 Recombinant Glycogen Synthase Kinase 3 Beta (GSK3b) Positive Control; Immunogen; SDS-PAGE; WB.
PAD317Hu01 Polyclonal Antibody to Glycogen Synthase Kinase 3 Beta (GSK3b) WB; IHC; ICC; IP.
MAD317Hu21 Monoclonal Antibody to Glycogen Synthase Kinase 3 Beta (GSK3b) WB; IHC; ICC; IP.
SED317Hu ELISA Kit for Glycogen Synthase Kinase 3 Beta (GSK3b) Enzyme-linked immunosorbent assay for Antigen Detection.
LMD317Hu Multiplex Assay Kit for Glycogen Synthase Kinase 3 Beta (GSK3b) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.