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Recombinant A Disintegrin And Metalloprotease 17 (ADAM17)

CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease

  • Product No.RPB555Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Predicted Molecular Mass29.6kDa
  • Accurate Molecular Mass30kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu221~Ser451 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder
  • Purity> 97%
  • Isoelectric Point5.6
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 187  US$ 468  US$ 936  US$ 2808  US$ 7020 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Int Wound J. From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. Pubmed:26991748
International Wound Journal From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases pubmed:26991748
Biomedical Research ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes. pubmed:28637950
Cytometry B Clin Cytom L‐Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia Pubmed: 30729673
Disease Markers Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results Pubmed: 31565100
Chem Biol Interact PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice Pubmed: 32866465
life High Levels of TNF-¦Á and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection
Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
RPB555Ra01 Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) Positive Control; Immunogen; SDS-PAGE; WB.
PAB555Ra01 Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) WB; IHC; ICC; IP.
MAB555Ra21 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) WB; IHC; ICC; IP.
SEB555Ra ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB555Ra Multiplex Assay Kit for A Disintegrin And Metalloprotease 17 (ADAM17) ,etc. by FLIA (Flow Luminescence Immunoassay) FLIA Kit for Antigen Detection.