Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)

CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease

Product No.PAB555Ra01
Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
SourcePolyclonal antibody preparation
HostRabbit
Potencyn/a
Ig Type IgG
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
LabelNone
Immunogen n/a
Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
TraitsLiquid
Concentration500µg/mL
Organism Species MoreHomo sapiens (Human), Mus musculus (Mouse)
ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
DownloadInstruction Manual
UOM 20µl100µl 200µl 1ml 10ml
FOB US$ 109 253 US$ 253 US$ 362 US$ 905 US$ 3620
For more details, please contact local distributors!

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine	Citations
Int Wound J.	From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. Pubmed:26991748
International Wound Journal	From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases pubmed:26991748
Biomedical Research	ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes. pubmed:28637950
Cytometry B Clin Cytom	L‐Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia Pubmed: 30729673
Disease Markers	Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results Pubmed: 31565100
Chem Biol Interact	PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice Pubmed: 32866465
life	High Levels of TNF-¦Á and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection

Catalog No.	Related products for research use of Rattus norvegicus (Rat) Organism species	Applications (RESEARCH USE ONLY!)
RPB555Ra01	Recombinant A Disintegrin And Metalloprotease 17 (ADAM17)	Positive Control; Immunogen; SDS-PAGE; WB.
PAB555Ra01	Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)	WB; IHC; ICC; IP.
MAB555Ra21	Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)	WB; IHC; ICC; IP.
SEB555Ra	ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMB555Ra	Multiplex Assay Kit for A Disintegrin And Metalloprotease 17 (ADAM17) ,etc. by FLIA (Flow Luminescence Immunoassay)	FLIA Kit for Antigen Detection.