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Monoclonal Antibody to Urocortin 2 (UCN2)

URP; SRP; UCN-II; UCNII; Stresscopin-Related Peptide; Urocortin-related peptide

  • Product No.MAC585Hu27
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceMonoclonal antibody preparation
  • HostMouse
  • Potency (Clone Number)C11
  • Ig Isotype IgG
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
  • Concentration1mg/mL
  • Organism Species Moren/a
  • ApplicationsWB; IHC; ICC; IP.
    If the antibody is used in flow cytometry, please check FCM antibodies.
  • Downloadn/a
  • UOM 20µl100µl 200µl 1ml 10ml
  • FOB US$ 112  US$ 261  US$ 373  US$ 933  US$ 3730 
    For more details, please contact local distributors!

SPECIFITY

The antibody is a mouse monoclonal antibody raised against UCN2. It has been selected for its ability to recognize UCN2 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
Clin Chem. High-Sensitivity Sandwich ELISA for Plasma NT-proUcn2: Plasma Concentrations and Relationship to Mortality in Heart Failure. Pubmed:27127183
Clinica Chimica Acta Urocortins: Actions in health and heart failure pubmed:28887029
Cardiovascular Research Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension Pubmed:29584808
Journal of Neuroendocrinology Glucocorticoid withdrawal affects stress‐induced changes in urocortin 2 gene expression in the rat adrenal medulla and brain Pubmed:29604138
High Blood Press Cardiovasc Prev Evaluation of Serum Urocortin 2 Levels in Patients with Hypertension Pubmed: 31925709
CURRENT PROBLEMS IN CARDIOLOGY Urocortin-2 in acute heart failure: role as a marker of volume overload and pulmonary hypertension 33994037
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KSC585Hu01 ELISA Kit DIY Materials for Urocortin 2 (UCN2) Main materials for "Do It (ELISA Kit) Yourself".