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Monoclonal Antibody to Serotonin Transporter (SERT)

SLC6A4; SLC6-A4; HTT; 5-HTT; 5HTT; OCD1; hSERT; Solute Carrier Family 6,Member 4; Neurotransmitter Transporter,Serotonin; Sodium-dependent serotonin transporter

SPECIFITY

The antibody is a mouse monoclonal antibody raised against SERT. It has been selected for its ability to recognize SERT in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-3µg/mL
Immunohistochemistry: 5-30µg/mL
Immunocytochemistry: 5-30µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

GIVEAWAYS

INCREMENT SERVICES

Magazine Citations
Journal of Prosthodontic Research Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control Pubmed:25127373
Frontiers in Behavioral Neuroscience? Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain Pubmed:25400562
Sleep Breath Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects PubMed: 26527205
PLoS One. Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived fromMouse P19 Embryonal Carcinoma Cells. pubmed:27861613
Herz-Hirn Interaktion im Mausmodell: Herzinsuffizienz nach Myokardinfarkt führt zu depressivem Verhalten bei Mäusen frontdoor:index
Effects of Junk Foods on Brain Neurotransmitters (Dopamine and Serotonin) and some Biochemical Parameters in Albino Rats article_1486_c0fa9f8afe5f70b407e7195bcfd55c70
Toxicology Reports Neuro-and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor … Pubmed:29854627
Journal of Taibah University for Science Neurotoxicity and inflammation induced by individual and combined exposure to iron oxide nanoparticles and silver nanoparticles
NEUROGASTROENTEROLOGY AND MOTILITY Effects of regulating gut microbiota on the serotonin metabolism in the chronic unpredictable mild stress rat model Pubmed: 31323174
Thrombosis Research VAMP8 and serotonin transporter levels are associated with venous thrombosis risk in a Spanish female population. Results from the RETROVE Project Pubmed: 31382081
Scientia Psychiatrica Neuronal Cell Death Induces Depressive Disorder in Rats Depression-Like Behaviors Caused by Chronic Stress
Journal of Immunology Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats 34568500
Biol Pharm Bull Targeting the oxytocin system to ameliorate early life depressive-like behaviors in maternally-separated rats 34349049
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