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Famsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796
On February 17, 2023,Yiguo Wang, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, China, and his team published a paper titled “Famsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796” in Cell Research. Their results demonstrate that communication between the intestine and other organs by a famsin-OLFR796 signaling axis is critical for metabolic adaptations to fasting.The kits [High Sensitive ELISA Kit for Fibroblast Growth Factor 15 (FGF15), HEL154Mu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the re......
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Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
On December 23, 2022,Hoi Leong Xavier Wong, School of Chinese Medicine, Hong Kong Baptist University, China, and his team published a paper titled “Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2” in Nature Communications. Their findings provide in vivo evidence demonstrating the contribution of ACE2 shedding to the etiology of COVID-19.The kits [ELISA Kit for Angiotensin I Converting Enzyme 2 (ACE2), SEB886Mu, SEB886Hu; ELISA Kit for Matrix Metalloproteinase 14 (MMP14), SEC056Mu, SEC056Hu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a glo......
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Efficacy of serum apelin and galectin-3 as potential predictors of mortality in severe COVID-19 patients
On January 12, 2023, Erdal İn, Department of Chest Diseases, Malatya Turgut Özal University Faculty of Medicine, Turkey, and his team published a paper titled “Efficacy of serum apelin and galectin-3 as potential predictors of mortality in severe COVID-19 patients”in Journal of Medical Virology. Their research shows that galectin-3 may be a simple, useful, and prognostic biomarker that can be utilized to predict patients at high risk of mortality in severe COVID-19 patients.The kits [ELISA Kit for Apelin (APLN), CED066Hu; ELISA Kit for Galectin 3 (GAL3), SEA303Hu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Apelin is a cardiopro......
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New progress in the treatment of acute kidney injury
Acute kidney injury (AKI) is a global health problem,whichaffects about 20% of hospital inpatients. The primary clinical causes of AKI consist of sepsis, and nephrotoxic medications, ischemia-reperfusion injury. Current therapies for AKI are supportive, and short-term mortality remains high. In those who survive an episode of AKI, 30% are left with chronic kidney disease (CKD). The remaining 70% that recover full kidney function are at about 28-fold increased risk of ultimately developing CKD. Both AKI and CKD are strongly and independently associated with incident cardiovascular disease, and together, these exert a substantial global socioeconomic burden. Recently, a number of literat......
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TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocyte homeostasis
On January 12, 2023,Xiangming Fang, Department of Anesthesiology and Intensive Care, The First Affiliated Hospital, Zhejiang University School of Medicine, China, and his team published a paper titled “TREM2hiresident macrophages protect the septic heart by maintaining cardiomyocyte homeostasis” in Nature Metabolism. Their findings suggest that the modulation of TREM2hicardiac-resident macrophages could serve as a therapeutic strategy for SICM.The kits [ELISA Kit for Atrial Natriuretic Peptide (ANP), SEA225Mu; ELISA Kit for N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP), SEA485Mu; ELISA Kit for Cardiac Troponin I (cTnI), SEA478Mu] of Cloud-Clone brand was chosed in this artic......
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Targeted microglia in the treatment of central nervous system related diseases
As resident macrophages of the central nervous system (CNS), microglia are associated with diverse functions essential to the developing and adult brain during homeostasis and disease.Microglia are now considered among the most versatile cells in the body, possessing the capacity to morphologically and functionally adapt to their ever-changing surroundings. Harmonious cell-cell communication involving microglia are considered crucial to maintain the healthy state of the tissue environment and to overcome pathology such as neuroinflammation. Analyses of such intercellular pathways have contributed to our understanding of the heterogeneous but context-associated microglial responses to e......